Impact of assisted reproductive technology on birth weight discordance in twins.
10.7499/j.issn.1008-8830.2307034
- VernacularTitle:辅助生殖技术对双胎出生体重不一致的影响
- Author:
Qiu-Ying LI
1
;
Hui ZHANG
1
;
Qian CHEN
1
;
Bi-Jun SHI
1
;
Xiao-Hua TAN
1
;
Qi-Liang CUI
1
Author Information
1. Department of Neonatology, Third Affiliated Hospital of Guangzhou Medical University/Guangzhou Key Laboratory of Neonatal Intestinal Diseases, Guangzhou 510150, China (Zhang H, Email: zhanghuigz@126. com).
- Publication Type:Journal Article
- Keywords:
Assisted reproductive technology;
Birth weight discordance;
Neonate;
Twins
- MeSH:
Pregnancy;
Infant, Newborn;
Female;
Humans;
Birth Weight;
Pregnancy Outcome;
Infant, Premature;
Infant, Low Birth Weight;
Pregnancy, Multiple;
Premature Birth/epidemiology*;
Retrospective Studies;
Population Surveillance;
Reproductive Techniques, Assisted/adverse effects*;
Pregnancy Complications
- From:
Chinese Journal of Contemporary Pediatrics
2023;25(12):1239-1245
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To explore the association between assisted reproductive technology (ART) and birth weight discordance in twins (BWDT).
METHODS:A retrospective analysis was conducted on twin infants born between January 2011 and December 2020 at the Third Affiliated Hospital of Guangzhou Medical University, with complete basic birth data. The impact of ART on the occurrence of BWDT was identified by the multivariate logistic regression analysis.
RESULTS:A total of 3 974 pairs of twins were included, with 1 431 conceived naturally and 2 543 through ART. Neonates in the ART group had higher birth weights than those in the naturally conceived group (P<0.001). The incidence of BWDT was lower in the ART group compared to the naturally conceived group (16.17% vs 21.09%, P<0.001). The multivariate logistic regression analysis, adjusting for confounding factors such as maternal age, parity, pre-pregnancy body mass index, gestational diabetes, hypothyroidism, gestational age, and chorionic properties, showed no significant difference in the risk of BWDT between the ART and naturally conceived groups (P>0.05).
CONCLUSIONS:ART is not associated with the risk of BWDT.
