Decline in semen concentration of healthy Chinese adults: evidence from 9357 participants from 2010 to 2015.

Hong-fang Yuan; Huang-fang Shangguan; Yi Zheng; Tian-qing Meng; Cheng-liang Xiong; Huang-tao Guan

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Decline in semen concentration of healthy Chinese adults: evidence from 9357 participants from 2010 to 2015.

Author: Hong-Fang YUAN ¹ ; Huang-Fang SHANGGUAN ² ; Yi ZHENG ³ ; Tian-Qing MENG ⁴ ; Cheng-Liang XIONG ¹ ; Huang-Tao GUAN ¹
Author Information

1. Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
2. College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.
3. Department of Venereology, Wuhan Institute of Dermatology and Venereology, Wuhan 430031, China.
4. Reproductive Medicine Center, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Publication Type:Journal Article
Keywords: healthy men; semen concentration; sperm donors; temporal trends
MeSH: Adult; Aging; China/epidemiology*; Cohort Studies; Healthy Volunteers; Humans; Male; Retrospective Studies; Semen Analysis; Sperm Count; Tissue Donors; Young Adult
From: Asian Journal of Andrology 2018;20(4):379-384
CountryChina
Language:English
Abstract: The present study aims to analyze sperm concentration trends among young and healthy Chinese adults in Wuhan, Central China, from 2010 to 2015. Semen analysis data from 9357 participants were collected and analyzed using a general linear model and the Cochran-Armitage trend test. A significant decline was observed in sperm concentration (β [standard deviation]: -1.53 [0.16]; P < 0.001). In addition, a decline in sperm density was observed by stratifying student versus nonstudent sperm donors and by analyzing the year of birth or birth year cohort of the participants. Furthermore, the percentage of participants with sperm densities of over 40 × 10⁶ ml^-1 significantly decreased with year. Notably, a dramatic decline in sperm density was recorded over the first 5 years of study. This research reported a decline in sperm concentration among young adults in Wuhan, Central China, in 2010-2015.