Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique.
- Author:
Dae Yul YANG
1
;
Kyungtae KO
1
;
Seong Ho LEE
1
;
Du Geon MOON
2
;
Jong Wook KIM
2
;
Won Ki LEE
1
Author Information
- Publication Type:Multicenter Study
- MeSH: Adult; Aged; Cross-Linking Reagents; Dextrans/therapeutic use*; Follow-Up Studies; Gels; Humans; Injections; Male; Middle Aged; Patient Satisfaction; Penis/anatomy & histology*; Prospective Studies; Treatment Outcome; Young Adult
- From: Asian Journal of Andrology 2018;20(1):80-84
- CountryChina
- Language:English
- Abstract: There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm2 and 33.6 ± 5.4 cm2 , respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.
