Research progress of platelet bacteriostatic effects.
- Author:
Wenhua WANG
1
;
Lili XING
2
;
Ting MA
2
;
Jiangcun YANG
3
;
Xucang WEI
4
Author Information
1. Xi'an Medical University, Xi'an 710068, China.
2. Department of Blood Transfusion, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
3. Department of Blood Transfusion, Shaanxi Provincial People's Hospital, Xi'an 710068, China. *Corresponding authors, E-mail: yjc65@sina.com.
4. Department of Hematology Laboratory, Shaanxi Provincial People's Hospital, Xi'an 710068, China. *Corresponding authors, E-mail: weixucang62@sina.com.
- Publication Type:Journal Article
- MeSH:
Blood Platelets;
Anti-Bacterial Agents/pharmacology*;
Cytokines;
Leukocytes;
Particulate Matter
- From:
Chinese Journal of Cellular and Molecular Immunology
2023;39(9):857-862
- CountryChina
- Language:Chinese
-
Abstract:
Platelets not only have hemostatic function, but can also directly or indirectly recognize pathogenic microorganisms and the signals they produce to capture and destroy them through membrane receptors. They can collaborate with various components of the body's immune system by releasing of intraplatelet particulate matter, cytokines and chemokines to perform bactericidal functions. And it can also play a bactericidal role by swallowing pathogens, releasing antimicrobial proteins and chemokines and activating and enhancing other specialized anti-inflammatory cells bactericidal effect, such as leukocytes and so on. However, the bacteriostatic composition and bacteriostatic mechanism of platelets remain unclear, so attention should be paid to the immune mechanism and bacteriostatic effect of platelets.
