PCR Detection of the DNA Polymerase I Gene of Treponema pallidum from a Case of Atypical Primary Syphilis.
- Author:
Gilho LEE
1
;
Insoo RHEEM
Author Information
1. Department of Urology, Dankook University College of Medicine, Cheonan, Korea.
- Publication Type:Original Article
- Keywords:
Syphilis;
DNA polymerase I;
PCR
- MeSH:
Chancre;
DNA Polymerase I*;
Humans;
Male;
Penicillin G Benzathine;
Penis;
Polymerase Chain Reaction*;
Serologic Tests;
Sexually Transmitted Diseases;
Specialization;
Syphilis*;
Treponema pallidum*;
Ulcer
- From:The Korean Journal of Laboratory Medicine
2003;23(6):401-404
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Syphilis is easily diagnosed by serologic testing or by identification of the causative organism, Treponema pallidum. Syphilis usually presents a distinct painless primary ulcer or chancre. However, the initial clinical impressions of even the most experienced specialist in sexually transmitted diseases (STDs), may be wrong 40% of the time. We report a case of atypical primary syphilis that was presented with painful ulceration on the penis and showing negative VDRL results. We amplified the DNA polymerase I gene of Treponema pallidum in the penile ulcer lesion to detect syphilis and got the a successful result. The patient was treated with benzathine penicillin G.
