Research progress in influence of microstructure on performance of triply-periodic minimal surface bone scaffolds.
10.7507/1002-1892.202305004
- Author:
Yadi SUN
1
;
Jianxiong MA
1
;
Yan WANG
1
;
Benchao DONG
1
;
Peichuan YANG
1
;
Yan LI
1
;
Yiyang LI
1
;
Liyun ZHOU
1
;
Jiahui SHEN
1
;
Xinlong MA
1
Author Information
1. Institute of Orthopaedics, Tianjin Hospital, Tianjin University (Tianjin Hospital), Tianjin, 300211, P. R. China.
- Publication Type:Journal Article
- Keywords:
Triply-periodic minimal surface;
bone scaffold;
microstructure;
property
- MeSH:
Tissue Scaffolds/chemistry*;
Tissue Engineering/methods*;
Bone and Bones;
Porosity
- From:
Chinese Journal of Reparative and Reconstructive Surgery
2023;37(10):1314-1318
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To summarize the influence of microstructure on performance of triply-periodic minimal surface (TPMS) bone scaffolds.
METHODS:The relevant literature on the microstructure of TPMS bone scaffolds both domestically and internationally in recent years was widely reviewed, and the research progress in the imfluence of microstructure on the performance of bone scaffolds was summarized.
RESULTS:The microstructure characteristics of TPMS bone scaffolds, such as pore shape, porosity, pore size, curvature, specific surface area, and tortuosity, exert a profound influence on bone scaffold performance. By finely adjusting the above parameters, it becomes feasible to substantially optimize the structural mechanical characteristics of the scaffold, thereby effectively preempting the occurrence of stress shielding phenomena. Concurrently, the manipulation of these parameters can also optimize the scaffold's biological performance, facilitating cell adhesion, proliferation, and growth, while facilitating the ingrowth and permeation of bone tissue. Ultimately, the ideal bone fusion results will obtain.
CONCLUSION:The microstructure significantly and substantially influences the performance of TPMS bone scaffolds. By deeply exploring the characteristics of these microstructure effects on the performance of bone scaffolds, the design of bone scaffolds can be further optimized to better match specific implantation regions.
