Progress and prospect of biological treatment for rotator cuff injury repair.
10.7507/1002-1892.202303122
- Author:
Zhengbo YIN
1
;
Zhian CHEN
1
;
Ni YIN
2
;
Yifei ZHU
3
;
Bihuan ZHANG
1
;
Tianhua ZHOU
4
;
Hongbo TAN
4
;
Yongqing XU
4
Author Information
1. Graduate School of Kunming Medical University, Kunming Yunnan, 650500, P. R. China.
2. Department of Renal Rheumatology Immunology, the Third Xiangya Hospital of Central South University, Changsha Hunan, 410013, P. R. China.
3. Graduate School of Dali University, Dali Yunnan, 671003, P. R. China.
4. Department of Orthopedics, 920th Hospital of Joint Logistics Support Force of Chinese PLA, Kunming Yunnan, 650032, P. R. China.
- Publication Type:Journal Article
- Keywords:
Rotator cuff injury;
biotherapy;
exosome;
growth factor;
platelet rich plasma;
stem cells
- MeSH:
Humans;
Rotator Cuff Injuries/therapy*;
Quality of Life;
Arthroplasty;
Exosomes;
Neurosurgical Procedures
- From:
Chinese Journal of Reparative and Reconstructive Surgery
2023;37(9):1169-1176
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To review the research progress in biotherapy of rotator cuff injury in recent years, in order to provide help for clinical decision-making of rotator cuff injury treatment.
METHODS:The literature related to biotherapy of rotator cuff injury at home and abroad in recent years was widely reviewed, and the mechanism and efficacy of biotherapy for rotator cuff injury were summarized from the aspects of platelet-rich plasma (PRP), growth factors, stem cells, and exosomes.
RESULTS:In order to relieve patients' pain, improve upper limb function, and improve quality of life, the treatment of rotator cuff injury experienced an important change from conservative treatment to open surgery to arthroscopic rotator cuff repair. Arthroscopic rotator cuff repair plus a variety of biotherapy methods have become the mainstream of clinical treatment. All kinds of biotherapy methods have ideal mid- and long-term effectiveness in the repair of rotator cuff injury. The biotherapy method to promote the healing of rotator cuff injury is controversial and needs to be further studied.
CONCLUSION:All kinds of biotherapy methods show a good effect on the repair of rotator cuff injury. It will be an important research direction to further develop new biotherapy technology and verify its effectiveness.
