Progress in preparation and application of sodium alginate microspheres.
10.7507/1001-5515.202211048
- Author:
Xuanyu LIU
1
;
Yuhui WANG
1
;
Ziwei LIANG
1
;
Xiaojie LIAN
1
;
Di HUANG
1
;
Yinchun HU
1
;
Yan WEI
1
Author Information
1. Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P. R. China.
- Publication Type:Review
- Keywords:
Biocompatibility;
Bone repair;
Drug delivery;
Hemostasis;
Sodium alginate microsphere
- MeSH:
Alginates;
Biocompatible Materials;
Drug Delivery Systems;
Microspheres;
Plastic Surgery Procedures
- From:
Journal of Biomedical Engineering
2023;40(4):792-798
- CountryChina
- Language:Chinese
-
Abstract:
Sodium alginate (SA) is a kind of natural polymer material extracted from kelp, which has excellent biocompatibility, non-toxicity, biodegradability and abundant storage capacity. The formation condition of sodium alginate gel is mild, effectively avoiding the inactivation of active substances. After a variety of preparation methods, sodium alginate microspheres are widely used in the fields of biomaterials and tissue engineering. This paper reviewed the common methods of preparing alginate microspheres, including extrusion, emulsification, electrostatic spraying, spray drying and coaxial airflow, and discussed their applications in biomedical fields such as bone repair, hemostasis and drug delivery.
