Pharmacological research progress of five classical prescriptions in treatment of chronic heart failure.
10.19540/j.cnki.cjcmm.20230719.201
- Author:
Xin-Yu CHU
1
;
Xiao-Hong WEI
1
;
Xue-Fen WU
1
;
Jie CHEN
1
;
Huan XIA
1
;
Gui-Yang XIA
1
;
Sheng LIN
1
;
Hong-Cai SHANG
1
Author Information
1. Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital,Beijing University of Chinese Medicine Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
benefiting Qi and activating blood circulation;
chronic heart failure;
eliminating phlegm and dampness;
enhancing Qi and nourishing Yin;
rescuing from collapse by restoring Yang;
warming Yang for diuresis
- MeSH:
Humans;
Medicine, Chinese Traditional;
Heart Failure/drug therapy*;
Chronic Disease;
Syndrome
- From:
China Journal of Chinese Materia Medica
2023;48(23):6324-6333
- CountryChina
- Language:Chinese
-
Abstract:
Chronic heart failure(CHF) is a comprehensive clinical syndrome caused by multiple factors that result in structural and/or functional abnormalities of the heart, leading to impaired ventricular contraction and/or relaxation functions. This medical condition represents the final stage of various cardiovascular diseases. In the treatment of CHF, multiple clinical studies have demonstrated the benefits of using traditional Chinese medicine(TCM) to control oxidative stress, inflammation, and apoptosis, thereby delaying ventricular remodeling and reducing myocardial fibrosis. In this study, common TCM syndromes in the diagnosis and treatment of CHF in recent years were reviewed and summarized. Five common treatment methods including benefiting Qi and activating blood circulation, enhancing Qi and nourishing Yin, warming Yang for diuresis, eliminating phlegm and dampness, rescuing from collapse by restoring Yang, and corresponding classic prescriptions in prevention and treatment of CHF were concluded under the guidance of TCM syndrome differentiation thinking. Meanwhile, research progress on the modern pharmacological effects of these classic prescriptions was systematically discussed, so as to establish a unique treatment system for CHF by classic prescriptions under the guidance of TCM syndrome differentiation theory and provide innovative diagnosis and treatment strategies for clinical CHF.
