A new allo-aromadendrane sesquiterpene from Dendrobium nobile.
10.19540/j.cnki.cjcmm.20230721.201
- Author:
Jun-Hao WANG
1
;
Wen-Xu LU
1
;
Si-Jia WU
1
;
Jian LI
2
;
Zheng-Tao WANG
1
;
Hong XU
1
Author Information
1. the Ministry of Education Key Laboratory for Standardization of Chinese Medicines, the State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Medicine, Shanghai R&D Center for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
2. Jinling Pharmaceutical Co., Ltd. Nanjing 210009, China.
- Publication Type:Journal Article
- Keywords:
Dendrobium nobile;
chemical constituents;
sesquiterpenes;
soltorvum F
- MeSH:
Dendrobium/chemistry*;
Molecular Structure;
Sesquiterpenes, Guaiane;
Sesquiterpenes/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(22):6088-6092
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents in the non-alkaloid part of stems of Dendrobium nobile. The macroporous adsorption resin, MCI, silica gel, RP-C_(18), and Sephadex LH-20 gel, preparative thin layer chromatography, and preparative high-performance liquid chromatography(HPLC) were used to isolate and purify the compounds. The structures of the compound were determined according to the spectra data, physicochemical properties, and relevant references. A total of 8 compounds were isolated from D. nobile, which were soltorvum F(1), p-hydroxyphenylpropionic acid(2), vanillic acid(3), p-hydroxybenzoic acid(4), N-trans-cinnamic acid acyl-p-hydroxybenzene ethylamine(5),(+)-(1R,2S,3R,4S,5R,6S,9R)-2,11,12-trihydroxypicrotoxane-3(15)-lactone(6), dendronobilin H(7), soltorvum E(8). Compound 1 was a novel compound, named as soltorvum F. Compound 8 was isolated from Dendrobium species for the first time.
