Chemical constituents of Lindera aggregata and their bioactivities: a review.
10.19540/j.cnki.cjcmm.20221114.203
- Author:
Fang-You CHEN
1
;
Yang LIU
1
;
Dan XIE
1
;
Yong-Ming LUO
1
Author Information
1. School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.
- Publication Type:Journal Article
- Keywords:
Lindera aggregata;
alkaloids;
bioactivities;
sesquiterpenoid dimer;
sesquiterpenoids
- MeSH:
Lindera/chemistry*;
Alkaloids;
Flavonoids;
Antioxidants;
Sesquiterpenes/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(21):5719-5726
- CountryChina
- Language:Chinese
-
Abstract:
The medicinal Lindera aggregata(Lindera, Lauraceae) boasts abundant resources, which is widely used in clinical settings. It has been found that the main chemical constituents of this medicinal species are sesquiterpenoids, alkaloids, sesquiterpenoid dimers, flavonoids, and phenolic acids. Some unreported novel structures, including lindenane-type sesquiterpene dimers and trimers, have been discovered from L. aggregata in recent years. The extracts and active components of L. aggregata have anti-tumor, anti-inflammatory, antalgic, liver-protecting, antioxidant, lipid-lowering, and glucose-lowering activities, and their mechanisms of action have been comprehensively investigated. This study summarizes the research on the chemical constituents and bioactivities of L. aggregata over the past decade, which is expected to serve as a reference for the future research and utilization of L. aggregata.