Research progress in chemical constituents, pharmacological effects, and clinical application of Curcuma wenyujin and prediction of its quality markers.
10.19540/j.cnki.cjcmm.20230714.201
- Author:
Xing-Chen LI
1
;
Li-Yan YIN
1
;
Hong CAI
2
;
Xin-Yi LI
2
;
Xiao-Ying JI
2
;
Yi-Ying ZENG
2
;
Zhao-Wu ZENG
2
;
Tian XIE
1
Author Information
1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University Guangzhou 510006, China School of Pharmacy, Hangzhou Normal University Hangzhou 311121, China Key Laboratory of Elemene Class Anti-cancer Chinese Medicine of Zhejiang Province Hangzhou 311121, China Engineering Laboratory of Development and Application of Traditional Chinese Medicinal from Zhejiang Province Hangzhou 311121, China 2011 Collaborative Innovation Center of Chinese Medicines from Zhejiang Province Hangzhou 311121, China.
2. School of Pharmacy, Hangzhou Normal University Hangzhou 311121, China Key Laboratory of Elemene Class Anti-cancer Chinese Medicine of Zhejiang Province Hangzhou 311121, China Engineering Laboratory of Development and Application of Traditional Chinese Medicinal from Zhejiang Province Hangzhou 311121, China 2011 Collaborative Innovation Center of Chinese Medicines from Zhejiang Province Hangzhou 311121, China.
- Publication Type:Journal Article
- Keywords:
Curcuma wenyujin;
chemical constituents;
clinical application;
pharmacological effects;
quality control;
quality markers
- MeSH:
Anti-Inflammatory Agents;
Curcuma/chemistry*;
Liver
- From:
China Journal of Chinese Materia Medica
2023;48(20):5419-5437
- CountryChina
- Language:Chinese
-
Abstract:
Curcuma wenyujin, as one of the eight Daodi-herbs in Zhejiang province, is widely used. It has the effects of eliminating stasis and dissipating mass, moving Qi and activating blood, and clearing heart and relieving depression. Modern studies have shown that it has anti-tumor, anti-inflammatory, anti-oxidation, anti-thrombus and liver-protecting effects and mainly contains sesquiterpenoids, monoterpenoids, diterpenoids, and curcumins. This paper reviews the research progress in the chemical constituents and pharmacological effects of C. wenyujin in the last decade, discusses the modern clinical applications combined with the traditional efficacy, and predicts its quality markers(Q-markers) from plant consanguinity, medicinal properties, efficacy, processing and measurability of chemical components based on the theory of Q-markers, so as to provide a reference for the establishment of a scientific quality evaluation system and the research and application of this herb in the future.
