A Case of Transcatheter Alcohol Ablation of the Septum in a Patient of Hypertrophic Obstructive Cardiomyopathy.
10.4070/kcj.1998.28.6.1025
- Author:
Yeong Jun KIM
1
;
Won Ho JUNG
;
Sang Jin CHOI
;
Kyung Leem CHOI
;
En A KIM
;
Jung Ku LEE
;
Dong Kyu JIN
;
Qun DANG
;
Se Jin OH
;
Min Soo SON
;
Ji Won SON
;
In Suk CHOI
;
Eak Kyun SHIN
Author Information
1. Division of Cardiology Heart Center, Gachon Medical College, Gil Medical Center, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Dynamic LVOT obstruction;
Interventional infarction
- MeSH:
Arteries;
Cardiomyopathy, Hypertrophic*;
Catheters;
Coronary Vessels;
Heart Ventricles;
Humans;
Hypertrophy;
Infarction
- From:Korean Circulation Journal
1998;28(6):1025-1030
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by inappropriate myocardial hypertrophy that occurred in the absence of an obvious cause for the hypertrophy and dynamic left ventricular outflow tract obstruction, caused by asymmetrical septal hypertrophy and systolic anterior motion of the anterior mitral leaflet. The pathophysiological abnormality in HOCM is diastolic dysfunction, abnormal stiffness of the left ventricle with resultant impaired ventricular filling and impaired vasodilator reserve (perhaps related to the thickened and narrowed small intramural coronary arteries found in HOCM). During the early course of this progressive disease, treatment consists of negative inotropic drugs. Surgery has been the only therapeutic option in patients with hypertrophic cardiomyopathy who are resistant to drug treatment and sequential pacemaker therapy. We describe a novel catheter-based technique that may replace surgical myocardial reduction. The technique is interventional infarction of a portion of the interventricular septum by the infusion of alcohol into a selectively catheterized septal artery.
