Advances in pharmacological effects of jujuboside B.
10.19540/j.cnki.cjcmm.20230320.701
- Author:
Xiao-Na DONG
1
;
Meng-Ting LI
1
;
Hui-Yang GU
2
;
Ye ZHU
3
;
Xiang GU
3
Author Information
1. Medical College,Yangzhou University Yangzhou 225009,China.
2. Dalian Medical University Dalian 116044,China.
3. Department of Cardiology,Northern Jiangsu People's Hospital Yangzhou 225001,China.
- Publication Type:Journal Article
- Keywords:
anti-inflammatory;
antiplatelet;
antitumor;
jujuboside B;
pharmacological effects;
sedative and hypnotic
- MeSH:
Humans;
Drugs, Chinese Herbal/pharmacology*;
Saponins/pharmacology*;
Hypnotics and Sedatives;
Sleep Initiation and Maintenance Disorders;
Ziziphus/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(16):4295-4301
- CountryChina
- Language:Chinese
-
Abstract:
Ziziphi Spinosae Semen(ZSS) is an edible TCM derived from the dried ripe seeds of Ziziphus jujube Mill. var. spinosa(Bunge)Hu ex H. F. Chou(Rhamnaceae), which has the effects of nourishing the heart, tonifying the liver, calming the heart, tranquilizing the mind, arresting sweating, and promoting fluid production, and is widely used in the treatment and health care of diseases related to cardiovascular, nervous, and immune systems. Jujuboside B(JuB), one of the main active ingredients of ZSS, possesses various pharmacological effects with application values. This paper reviewed the chemical structure and pharmacological effects of JuB. JuB has sedative, hypnotic, antitumor, anti-platelet, anti-inflammatory, and other biological activities, which shows the potential thera-peutic effects on insomnia, tumors, coronary artery disease, airway inflammation, and liver injury. However, there are some limitations to the results of current studies. More comprehensive studies, including basic research and clinical trials, need to be carried out to provide more reliable evidence.
