A new norsesquiterpenoid from Arctium lappa leaves.
10.19540/j.cnki.cjcmm.20230517.202
- Author:
Jiang-Nan LYU
1
;
Ling-Xia ZHANG
1
;
Qing-Yu YANG
1
;
Na HUANG
1
;
Zhi-Min WANG
2
;
Li-Ping DAI
1
Author Information
1. Henan University of Chinese Medicine Zhengzhou 450046, China Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province, Henan University of Chinese Medicine Zhengzhou 450046, China.
2. Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province, Henan University of Chinese Medicine Zhengzhou 450046, China National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Arctium lappa leaves;
chemical constituents;
norsesquiterpenoid;
structural identification
- MeSH:
Arctium/chemistry*;
Magnetic Resonance Spectroscopy;
Luteolin/analysis*;
Plant Leaves/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(18):5024-5031
- CountryChina
- Language:Chinese
-
Abstract:
Chemical constituents were isolated and purified from ethyl acetate fraction of Arctium lappa leaves by silica gel, ODS, MCI, and Sephadex LH-20 column chromatography. Their structures were identified with multiple spectroscopical methods including NMR, MS, IR, UV, and X-ray diffraction combined with literature data. Twenty compounds(1-20) were identified and their structures were determined as arctanol(1), citroside A(2), melitensin 15-O-β-D-glucoside(3), 11β,13-dihydroonopordopicrin(4), 11β,13-dihydrosalonitenolide(5), 8α-hydroxy-β-eudesmol(6), syringin(7), dihydrosyringin(8), 3,4,3',4'-tetrahydroxy-δ-truxinate(9),(+)-pinoresinol(10), phillygenin(11), syringaresinol(12), kaeperferol(13), quercetin(14), luteolin(15), hyperin(16), 4,5-O-dicaffeoylquinic acid(17), 1H-indole-3-carboxaldehyde(18), benzyl-β-D-glucopyranoside(19), and N-(2'-phenylethyl) isobutyramide(20). Among them, compound 1 is a new norsesquiterpenoid, and compounds 2-5, 7-8, and 18-20 are isolated from this plant for the first time.
