A new nor-sesquiterpene glycoside from Corydalis edulis.
10.19540/j.cnki.cjcmm.20191104.202
- Author:
Zhi-Tian PENG
1
;
Ling-Hui CHAO
1
;
Chao-Chao WANG
1
;
Hui XIA
1
;
Di-Fa LIU
2
;
Zhang-Wei WANG
2
;
Jiao ZHENG
1
;
Yun-Fang ZHAO
1
;
Peng-Fei TU
1
;
Jun LI
1
Author Information
1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
2. State Key Laboratory of Innovative Natural Medicine and Traditional Chinese Medicine Injections, Jiangxi Qingfeng Pharmaceutical Co., Ltd. Ganzhou 341000, China.
- Publication Type:Journal Article
- Keywords:
Corydalis edulis;
absolute configuration;
chemical constituents;
electronic circular dichroism;
nor-sesquiterpene glycoside
- MeSH:
Chromatography, High Pressure Liquid;
Corydalis/chemistry*;
Glycosides/isolation & purification*;
Molecular Structure;
Phytochemicals/isolation & purification*;
Sesquiterpenes/isolation & purification*
- From:
China Journal of Chinese Materia Medica
2020;45(3):579-583
- CountryChina
- Language:Chinese
-
Abstract:
This study is to investigate the chemical constituents from the whole plant Corydalis edulis. The chemical constituents were separated and purified by macroporous resin D101, silica gel, Sephadex LH-20, ODS, and semi-preparative HPLC. Their structures were determined by physicochemical properties and spectroscopic data. Four compounds were isolated from the dichloromethane and water extracts of the whole plant C. edulis, and identified as 6'-β-D-xylosylicariside B2(1),(3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-megastigmen-9-one(2), loliolide(3), and 5,5'-dimethoxybiphenyl-2,2'-diol(4), respectively. Compound 1 is a new compound, of which the absolute configuration was established by electronic circular dichroism(ECD) calculations. Compound 4 is obtained from the plants of Papaveraceae family for the first time. Compounds 2 and 3 are firstly isolated from the Corydalis genus.
