Fermentation of cellulase with multiple types of Salvia miltiorrhiza residues and other solid wastes from Chinese materia medica industrialization.
10.19540/j.cnki.cjcmm.20191217.303
- Author:
Shou-Zhe QIU
1
;
Fei ZENG
1
;
Sen ZHANG
1
;
Shu-Lan SU
1
;
Sheng GUO
1
;
Da-Wei QIAN
1
;
Ming-Zhe ZHAO
1
;
Jin-Ao DUAN
1
Author Information
1. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Key Laboratory of Chinese Medicinal Resources Recycling Utilization under State Administration of Traditional Chinese Medicine,National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine Nanjing 210023, China.
- Publication Type:Journal Article
- Keywords:
Penicillium expansum;
Salvia miltiorrhiza residues;
cellulase;
resources circulating utilization;
solid waste from Chinese materia medica industrialization
- MeSH:
Cellulase/biosynthesis*;
China;
Drug Industry;
Drugs, Chinese Herbal;
Fermentation;
Materia Medica;
Penicillium/metabolism*;
Salvia miltiorrhiza;
Solid Waste
- From:
China Journal of Chinese Materia Medica
2020;45(4):890-895
- CountryChina
- Language:Chinese
-
Abstract:
The solid wastes of Chinese materia dedica industrialization represented by Salvia miltiorrhiza residues have a strong small-molecule bio-recalcitrance in the process of high-value utilization of biotransformation. Highly tolerant strains were bred to break bio-recalcitrance of Salvia miltiorrhiza residues and produce high-value added cellulose, which has a significant significance for recycling and industrial utilization of solid waste. In this study, a strain of fungus, Penicillium expansum SZ13, was found with small-molecule antibacterial substance tanshinone contained in Salvia miltiorrhiza residues by a biological method. The optimal enzyme production process and peak period of SZ13 were determined. It was found that SZ13 could maintain peak enzyme production for 5 days by degrading residues under the conditions of temperature 35 ℃, rotation speed 180 r·min~(-1), 5% of residues addition, and 5% seed solution addition. Meanwhile, the ability of SZ13 to degrade the enzyme production of multiple types of residues was explored. The results showed a high enzyme activity and stable enzyme production of SZ13 in the process of degrading residues. SZ13 could efficiently utilize various types of Chinese medicine residues, such as Salvia miltiorrhiza residues, to realize the high-value utilization of cellulose in multiple types of residues.
