Effect of Açaí oil, alcohol extract and water extract on temperature tendency and metabolic level of mice with deficiency-feat and deficiency-cold.
10.19540/j.cnki.cjcmm.20190321.403
- Author:
Xue ZHOU
1
;
Na YUE
1
;
Shuo ZHANG
1
;
Zi-Nan ZHAO
2
;
Chun WANG
1
;
Lin-Yuan WANG
2
;
Jian-Jun ZHANG
1
Author Information
1. School of Basic Medical Science, Beijing University of Chinese Medicine Beijing 100029, China.
2. School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
- Publication Type:Journal Article
- Keywords:
Açaí alcohol extract;
Açaí oil;
Açaí water extract;
cyclic nucleotides;
material basis;
temperature tendency
- MeSH:
Animals;
Ethanol;
Euterpe/chemistry*;
Medicine, Chinese Traditional;
Mice;
Plant Extracts/pharmacology*;
Plant Oils/pharmacology*;
Random Allocation;
Temperature;
Water
- From:
China Journal of Chinese Materia Medica
2020;45(5):991-996
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the effect of resolution components, such as Açaí oil, alcohol extract and water extract, on the temperature tendency animal behavior and intrinsic biochemical indexes, such ascyclic nucleotides and metabolic level, in mice with deficiency-heat and deficiency-cold syndrome, in order to study the characteristics of the cold and heat properties of each resolution component of Açaí and the material basis of cooling. KM mice were randomly divided into 12 groups, namely blank group, deficiency-heat model group, deficiency-heat+Açaí group, deficiency-heat+Açaí oil group, deficiency-heat+Açaí alcohol extract group, deficiency-heat+Açaí water extract group, deficiency-cold model group, deficiency-cold+Cinnamomi Cortex group, deficiency-cold+Açaí group, deficiency-cold+Açaí oil group, deficiency-cold+Açaí alcohol extract group, deficiency-cold+Açaí water extract group. The mice in deficiency-heat group were given thyroid tablet solution(160 mg·kg~(-1)), the mice in deficiency-cold group were given hydrocortisone solution(25 mg·kg~(-1)) through gastric perfusion every afternoon for 14 days, and each administration group was given the corresponding drug. The temperature tendency, cyclic nucleotides and metabolic level of animals were measured after the experiment. The Açaí alcohol extract was consistent with the Açaí powder, with a regulatory effect on the deficiency-heat model mice; Açaí oil and its water extract were consistent with Cinnamomi Cortex, with a regulatory effect on the deficiency-cold model mice. In this study, based on the parable theory of traditional Chinese medicine's properties and tastes, property of alcohol extract of Açaí was cool, while the property of oil and water extract were warm, the alcohol extract of Açaí was the material basis of Açaí cold medicine by the methods of homogeneous comparison and heterogeneous disproval.
