Metabonomics research strategy based on microdialysis technique.
10.19540/j.cnki.cjcmm.20190830.502
- Author:
Ying-Feng ZHANG
1
;
Xing-Xing HUANG
1
;
Li-Xia ZHU
2
Author Information
1. College of Chinese Materia Medica, Guangzhou University of Traditional Chinese Medicine Guangzhou 510006, China.
2. Department of Traditional Chinese Medicine, Zhujiang Hospital, South Medical University Guangzhou 510282, China.
- Publication Type:Journal Article
- Keywords:
discussion;
metabonomics;
microdialysis technique;
research strategy
- MeSH:
Medicine, Chinese Traditional;
Metabolomics;
Microdialysis;
Research Design;
Systems Biology
- From:
China Journal of Chinese Materia Medica
2020;45(1):214-220
- CountryChina
- Language:Chinese
-
Abstract:
Metabonomics is the branch of systems biology. It has been widely used in the fields of diagnostic markers discovery, disease prognosis, drug action mechanism, drug efficacy and toxicity evaluation, traditional Chinese medicine syndromes differentiation. There are shortcomings in the conventional metabonomics research. Microdialysis technology is a new type of biosampling technology, and metabonomics research based on microdialysis technology is in the ascendant. In view of the particularity of microdialysis technology and its great differences from traditional sampling and pretreatment methods, the metabonomics process based on microdialysis technology has certain similarities with traditional metabonomics research, and its basic process has some particularity. Advantages and basic strategies of metabonomics research by microdialysis technology are systematically summarized for researchers' reference.
