Research progress on sesquiterpenes and its pharmacological activities in genus Carpesium.
10.19540/j.cnki.cjcmm.20190929.201
- Author:
Di-Lu CHEN
1
;
Xuan LI
1
;
Xiao-Jiang ZHOU
2
Author Information
1. Hunan University of Chinese Medicine Changsha 410208, China.
2. Hunan University of Chinese Medicine Changsha 410208, China Engineering Technology Research Center of Standardization and Function of Traditional Chinese Medicine Decoction Pieces in Hunan Province Changsha 410208, China.
- Publication Type:Review
- Keywords:
chemical structure;
genus Carpesium;
pharmacological activities;
sesquiterpene
- MeSH:
Anti-Bacterial Agents;
Anti-Inflammatory Agents;
Asteraceae/chemistry*;
Lactones;
Molecular Structure;
Phytochemicals/pharmacology*;
Sesquiterpenes/pharmacology*
- From:
China Journal of Chinese Materia Medica
2020;45(1):37-51
- CountryChina
- Language:Chinese
-
Abstract:
The genus Carpesium plants contain many kinds of sesquiterpenes. Up to now, more than 201 sesquiterpene compounds have been isolated and identified, including 86 germacranolides, 30 eudesmanolides, 29 guaianolides, 23 sesquiterpene dimers, 9 pseudoguaianes, 9 carabranolides, 7 xanthanolides, 6 sesquiterpenes without lactone, 1 eremophilane and 1 tricyclo dodecane sesquiterpene. The reported sesquiterpenes possess a series of pharmacological properties, such as anti-tumor, anti-inflammatory, antibacterial, antiparasitic, insecticidal, and antiviral activities. This paper summarizes the 201 chemical structures and biological activities of sesquiterpenes in genus Carpesium, and provides the scientific basis for the further development and utilization.
