Study on simultaneous determination of six arsenic species by HPLC-ICP-MS.
10.19540/j.cnki.cjcmm.20190830.201
- Author:
Yao-Lei LI
1
;
Ying WANG
1
;
Zhao WANG
1
;
Hong-Yu JIN
1
;
Shuang-Cheng MA
1
Author Information
1. National Institutes for Food and Drug Control Beijing 100050,China.
- Publication Type:Journal Article
- Keywords:
As(Ⅲ);
As(Ⅴ);
HPLC-ICP-MS;
arsenic;
hyphenated technique;
morphology of arsenic
- MeSH:
Arsenic/analysis*;
Arsenicals/analysis*;
Chromatography, High Pressure Liquid;
Mass Spectrometry
- From:
China Journal of Chinese Materia Medica
2019;44(24):5441-5445
- CountryChina
- Language:Chinese
-
Abstract:
This study aims to establish a method for the determination of As B,As C,DMA,As( Ⅲ),MMA and As( Ⅴ) by using HPLC-ICP-MS. A Dioncx Ion PacTMAS7( 4 mm×250 mm) column was used for the HPLC-ICP-MS method. The mobile phase was 100 mmol·L-1 ammonium carbonate-1. 5 mmol·L-1 ammonium dibasic phosphate( gradient elution) at a flow rate of 1 m L·min-1. The injection volume was 10 μL. The linear relationships of As B,As C,DMA,As( Ⅲ),MMA,As( Ⅴ) were good with the concentration of10-500 μg·L-1. The average recovery rates( n = 6) were 105. 7%,100. 5%,102. 9%,105. 7%,100. 2%,92. 69%. The RSD were0. 50%,2. 4%,0. 93%,1. 3%,0. 89%,1. 5%. The precision and repeatability of this method were good. In this study,six forms of arsenic were separated effectively by this method. With methodological validation and sample determination,this method can be used to determine the morphological valence of arsenic in content determination.
