Chemical constituents from ethyl acetate extraction of Prunus mume.
10.19540/j.cnki.cjcmm.20190828.201
- Author:
Can-Can WANG
1
;
Wei ZHANG
2
;
De-Ling WU
2
;
Feng-Qing XU
3
;
Jin-Song LIU
3
;
Jin-Wei QIAO
4
Author Information
1. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China.
2. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Key Laboratory of Xin'an Medicine, Ministry of Education Hefei 230012, China Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of the New Manufacturing Technology Hefei 230012, China.
3. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Key Laboratory of Xin'an Medicine, Ministry of Education Hefei 230012, China.
4. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Second Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230001, China.
- Publication Type:Journal Article
- Keywords:
Prunus mume;
SH-SY5Y cells;
chemical constituents
- MeSH:
Acetates;
Phytochemicals/analysis*;
Plant Extracts/chemistry*;
Prunus/chemistry*;
Solvents
- From:
China Journal of Chinese Materia Medica
2020;45(2):347-351
- CountryChina
- Language:Chinese
-
Abstract:
Eight compounds were isolated from the ethyl acetate extraction of Prunus mume by column chromatography. On the basis of physicochemical properties and spectrum analysis, these compounds were identified as isoquercitrin-6″-O-benzoate(1), pinoresinol(2), naringin(3), ethyl-β-D-glucopyranoside(4), astragalin(5), quercetin(6), hypericin(7), and rutin(8). Among them, compound 1 was a new natural product, and compounds 2-5 were isolated from this plant for the first time. In vitro study, compounds 1, 3, 5-8 could significantly increase the cell survival ratio.
