A new guaiane-type sesquiterpenoid from Croton yunnanensis.

Author: Hui-Mei YOU ¹ ; Juan-Rong ZHANG ¹ ; Zhi-Heng ZHAO ¹ ; Wei WANG ¹ ; Li-Zhu ZHANG ¹ ; Yun-Tao JIANG ¹ ; Ying WANG ¹ ; Xiang-Zhong HUANG ¹ ; Zhi-Yong JIANG ¹
Author Information

1. State Key Laboratory of Education Ministry-State Minority Committee of National Medicine Resource Chemistry,School of Ethnic Medicine,Yunnan Minzu University Kunming 650500,China.
Publication Type:Journal Article
Keywords: Croton yunnanensis; eudesmane; guaiane; sesquiterpenoids
MeSH: Croton; Magnetic Resonance Spectroscopy; Molecular Structure; Sesquiterpenes; Sesquiterpenes, Guaiane
From: China Journal of Chinese Materia Medica 2019;44(21):4648-4652
CountryChina
Language:Chinese
Abstract: Five sesquiterpenoids were isolated from 90% ethanol extract of Croton yunnanensis by silica gel,Sephadex LH-20 column chromatography,as well as prep-HPLC methods. Based on MS,1 D and 2 D NMR spectral analyses,the structures of the five compounds were identified as 11-methoxyl alismol(1),6β,7β-epoxy-4α-hydroxyguaian-10-ene(orientalol C,2),multisalactone D(3),arvestonol(4),and 4,5-dihydroblumenol A(5). Compound 1 was a new guaiane-type sesquiterpenoid. Compounds 2-4 were isolated from the Croton genus for the first time,and compound 5 was obtained from this plant for the first time.