Comparative study on standard decoctions of Ophiopogonis Radix and Liriopes Radix.
10.19540/j.cnki.cjcmm.20190804.306
- Author:
Peng ZHANG
1
;
Lan WU
2
;
Xi-Wen LI
2
;
An LIU
2
;
Xue ZHANG
3
;
Zong-Hua SONG
3
;
Shi-Lin CHEN
2
Author Information
1. Chinese Pharmacopoeia Commission Beijing 100061,China Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China School of Chinese Materia Medica,Beijing University of Chinese Medicine Beijing 102488,China.
2. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
3. Chinese Pharmacopoeia Commission Beijing 100061,China.
- Publication Type:Journal Article
- Keywords:
Ophiopogonis Radix from Zhejiang province(ZMD);
decoction standard;
pH;
quality control;
quality evaluation;
quality marker
- MeSH:
Drugs, Chinese Herbal;
Materia Medica;
Plant Roots;
Quality Control
- From:
China Journal of Chinese Materia Medica
2019;44(21):4612-4620
- CountryChina
- Language:Chinese
-
Abstract:
Standard decoction is the core of the pharmacodynamics for water-soluble substance of Chinese materia medica. Its research is of great significance to the research and development of some single ingredients and the classical prescriptions,and it is the only way to transform traditional medication experience into industrial products. In this article,standard decoction research strategies were used for the comparison analysis of Ophiopogonis Radix from Zhejiang province(ZMD),Ophiopogonis Radix from Sichuan province(CMD),and Liriopes Radix(SMD). Regularities were present among different grades of CMD; potential quality markers and pH differences associated with SO2 residues were also found. Finally,the extract powder of Ophiopogonis Radix prepared by mass production process was analyzed and validated,and the results showed that the standard system could be used for the quality control of intermediates and final products. In conclusion,this study can provide reference for the clinical application of Ophiopogonis Radix medicines and provide testing method for higher quality with higher price.
