Research methods and applications progress on spectrum-effect relationships in study of traditional Chinese medicine.
10.19540/j.cnki.cjcmm.20190429.201
- Author:
Xiao-Yi ZHANG
1
;
Jiu-Shi LIU
1
;
Shi-Man GAO
1
;
Rong-Chang CHEN
1
;
Yao-Dong QI
1
;
Ben-Gang ZHANG
1
;
Hai-Tao LIU
1
;
Pei-Gen XIAO
1
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100193,China.
- Publication Type:Journal Article
- Keywords:
Chinese medicinal spectrum-effect relationships;
chemical fingerprint;
multivariate statistical analysis;
pharmacodynamic evaluation
- MeSH:
Drugs, Chinese Herbal;
Medicine, Chinese Traditional;
Records;
Research Design
- From:
China Journal of Chinese Materia Medica
2019;44(20):4405-4411
- CountryChina
- Language:Chinese
-
Abstract:
The application of chemical fingerprint to evaluate the quality of traditional Chinese medicine has been widely accepted and used in many countries. However,only by analyzing the type and content of its chemical components to evaluate the quality of traditional Chinese medicines,the gold standard of quality evaluation by evaluating pharmacodynamic effects is ignored. The study of Chinese medicinal spectrum-effect relationships combining the chemical composition with the pharmacodynamic activity of traditional Chinese medicine,which can evaluate the quality of traditional Chinese medicine from more comprehensive and different angles,has been applied in many fields of traditional Chinese medicine research. This paper mainly summarizes the research methods of the Chinese medicinal spectrum-effect relationships and its application in the field of traditional Chinese medicine study,and provides reference for the research,development and application of the Chinese medicinal spectrum-effect relationships.
