Sporadic Creutzfeldt-Jakob Disease With Slow Progression:Report of One Case.
10.3881/j.issn.1000-503X.15280
- Author:
Jia-Hua ZHAO
1
;
Lei WU
1
;
Wei JIN
2
;
Qiu-Ping GUI
2
;
Jia-Tang ZHANG
1
;
De-Hui HUANG
1
Author Information
1. Department of Neurology,The First Medical Centre of Chinese PLA General Hospital,Beijing 100853,China.
2. Department of Pathology,The First Medical Centre of Chinese PLA General Hospital,Beijing 100853,China.
- Publication Type:Journal Article
- Keywords:
brain biopsy;
prion;
sporadic Creutzfeldt-Jakob disease
- MeSH:
Humans;
Creutzfeldt-Jakob Syndrome/pathology*;
Brain/pathology*;
Magnetic Resonance Imaging;
Central Nervous System/pathology*
- From:
Acta Academiae Medicinae Sinicae
2023;45(5):859-862
- CountryChina
- Language:Chinese
-
Abstract:
Sporadic Creutzfeldt-Jakob disease(sCJD)is a prion-caused degenerative disease of the central nervous system,with the typical clinical manifestation of rapidly progressive dementia.The course of disease is less than 1 year in most patients and more than 2 years in only 2% to 3% patients.We reported a case of sCJD with expressive language disorder and slow progression in this paper.By summarizing the clinical manifestations and the electroencephalograhpy,MRI,and pathological features,we aimed to enrich the knowledge about the sCJD with slow progression.
