Tiaoshen acupuncture for primary insomnia: a pilot randomized controlled trial.
10.13703/j.0255-2930.20221120-0001
- Author:
Yi-Shan HUO
1
,
2
;
Zhao-Yi CHEN
3
;
Xue-Jiao YIN
3
;
Tong-Fei JIANG
3
;
Gui-Ling WANG
3
;
Ying-Xue CUI
3
;
Jing GUO
3
Author Information
1. Acupuncture-Moxibustion Center, Beijing Hospital of TCM Affiliated to Capital Medical University, Beijing 100010, China
2. Department of TCM, First Affiliated Hospital of Tsinghua University, Beijing 100016.
3. Acupuncture-Moxibustion Center, Beijing Hospital of TCM Affiliated to Capital Medical University, Beijing 100010, China.
- Publication Type:Journal Article
- Keywords:
Montreal cognitive assessment (MoCA);
Pittsburgh sleep quality index (PSQI);
acupuncture;
cognitive function;
primary insomnia (PI);
sham acupuncture;
sleep quality
- MeSH:
Humans;
Pilot Projects;
Sleep Initiation and Maintenance Disorders/therapy*;
Acupuncture Therapy;
Cognition;
Fatigue
- From:
Chinese Acupuncture & Moxibustion
2023;43(9):1008-1013
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effects of Tiaoshen (regulating the spirit) acupuncture on cognitive function and sleep quality in patients with primary insomnia (PI).
METHODS:Sixty patients with PI were randomly divided into an observation group (30 cases, 2 cases dropped off) and a control group (30 cases, 2 cases dropped off, 1 case was excluded). The patients in the observation group were treated with acupuncture at Baihui (GV 20), Shenting (GV 24), Sishencong (EX-HN 1), and bilateral Benshen (GB 13), Shenmen (HT 7), Neiguan (PC 6), Sanyinjiao (SP 6). The patients in the control group were treated with shallow needling at non-effective points. Each treatment was provided for 30 min, once every other day, 3 treatments per week for 4 weeks. The Montreal cognitive assessment (MoCA), digit span test (DST), trail making test (TMT)-A, Pittsburgh sleep quality index (PSQI), and fatigue scale-14 (FS-14) were used to assess cognitive function and sleep quality before and after treatment, as well as in follow-up of 4-week after treatment completion. Correlation analysis was conducted between the differences in PSQI scores and differences in MoCA scores before and after treatment in the observation group.
RESULTS:Compared with before treatment, the total score, visuospatial and executive function score and delayed memory score of MoCA as well as DST backward score were increased (P<0.01), while TMT-A time, PSQI and FS-14 scores were significantly reduced (P<0.01) after treatment and in follow-up in the observation group. Compared with before treatment, the PSQI score in the control group was reduced (P<0.01, P<0.05). After treatment and in follow-up, the observation group had significantly higher total score, visuospatial and executive function score, delayed memory score of MoCA, and DST backward score compared to the control group (P<0.05, P<0.01). In the observation group, the TMT-A time was significantly shorter than that in the control group (P<0.05, P<0.01), and the PSQI and FS-14 scores were significantly lower than those in the control group (P<0.01). In the observation group, there was a negative correlation between the difference in PSQI scores (post-treatment minus pre-treatment) and the difference in MoCA scores (post-treatment minus pre-treatment) (r=-0.481, P<0.01). A similar negative correlation was found between the difference in PSQI scores (follow-up minus pre-treatment) and the difference in MoCA scores (follow-up minus pre-treatment) (r=-0.282, P<0.05).
CONCLUSION:Tiaoshen acupuncture could improve cognitive function, enhance sleep quality, and alleviate daytime fatigue in patients with PI. The improvement in cognitive function in patients with PI is correlated with the improvement in sleep quality.
