Effect of Lactobacillus crispatus on Female Reproductive Tract Health and Its Antibacterial and Anti-inflammatory Mechanisms
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).20240004.013
- VernacularTitle:卷曲乳杆菌对女性生殖道健康的影响及抑菌和抗炎机制
- Author:
Jiahui SUN
1
;
Liya SONG
1
Author Information
1. College of Chemistry and Materials Engineering， Beijing Technology and Business University， Beijing 100048， China
- Publication Type:Review
- Keywords:
Lactobacillus;
Lactobacillus crispatus;
genital tract health;
bacteriostatic;
anti-inflammatory
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(1):28-34
- CountryChina
- Language:Chinese
-
Abstract:
Lactobacilli are important colonizing bacteria in female reproductive tract， among which Lactobacillus crispatus is closely associated with reproductive tract health and plays a crucial role in maintaining the vaginal microbiota balance. A decrease in the abundance of Lactobacillus crispatus may be correlated with various female reproductive tract diseases， such as bacterial vaginosis and vulvovaginal candidiasis， and it can even lead to adverse pregnancy outcomes such as infertility and embryo arrest. This article provides an overview of the basic characteristics of Lactobacillus crispatus， relationship between the decrease of its quantity and reproductive tract diseases， its ability to inhibit pathogenic bacteria such as Candida albicans and Chlamydia trachomatis， and the anti-inflammatory effects of Lactobacillus crispatus. The aim is to provide references for the use of Lactobacillus crispatus in vaginal therapeutics.
