Application of Mendelian randomization in liver cancer
- VernacularTitle:孟德尔随机化在肝癌研究中的应用
- Author:
Lingwei LI
1
;
Junjie QIN
1
;
Yunlong JIA
2
;
Hao LYU
2
Author Information
- Publication Type:Review
- Keywords: Mendelian Randomization Analysis; Liver Neoplasms; Genome-Wide Association Study
- From: Journal of Clinical Hepatology 2024;40(2):391-396
- CountryChina
- Language:Chinese
- Abstract: In recent years， the research method of Mendelian randomization based on genome-wide association studies has been widely used for etiological exploration in the medical field， which can effectively overcome the confounding biases and interference of reverse causalities in traditional observational researches with its unique advantages of the distributive randomness and timing priority of genetic variants. This article reviews the method of Mendelian randomization and its application in liver cancer， in order to provide new ideas for the research on causal association in liver cancer.
