Study on the Development and Implementation of Electronic Patient Reported Outcome - Pharmaceutical Management System for Enhanced CINV Control -

Saori Kimura; Koichi Ohata; Hirotoshi Iihara; Sawako Nishioka; Rie Ozeki; Mitsue Saito; Tomoyuki Nakagawa; Masayo Komoda

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Study on the Development and Implementation of Electronic Patient Reported Outcome - Pharmaceutical Management System for Enhanced CINV Control -

VernacularTitle:CINV 対策充実を目指した電子患者日誌 ―薬学的管理システムの開発と実装研究―
Author: Saori KIMURA ¹ ; Koichi OHATA ² ; Hirotoshi IIHARA ² ; Sawako NISHIOKA ¹ ; Rie OZEKI ¹ ; Mitsue SAITO ³ ; Tomoyuki NAKAGAWA ⁴ ; Masayo KOMODA ¹
Author Information

1. Faculty of Pharmaceutical Sciences, Tokyo University of Science
2. Department of Pharmacy, Gifu University Hospital
3. Department of Breast Oncology, Juntendo University School of Medicine
4. Faculty of Science and Engineering, Tokyo University of Science
Keywords: chemotherapy; chemotherapy-induced nausea and vomiting; ePRO; electronic patient diary; pharmaceutical management system
From:Japanese Journal of Drug Informatics 2023;25(3):131-142
CountryJapan
Language:Japanese
Abstract: Objective: Chemotherapy-induced nausea and vomiting (CINV) can affect a patient’s quality of life and make them resistant to the treatment. We created an electronic patient reported outcome ePRO-linked pharmaceutical management system (PMS) for CINV (CINVePRO) for storing information, such as nausea and vomiting status, food intake, etc., and suggesting the type of anti-nausea medication and dosage changes to the physicians for controlling CINV.Design: At the Gifu University Hospital, the collaborative research institute, inpatients and pharmacists in charge used CINVePRO-PMS, and a questionnaire survey was done to assess the system’s reliability.Methods: The daily entry of data into CINVePRO shows the number and duration of vomiting, degree of nausea, and amount of food consumed and displays a list and graph of these data over time. The PMS enables pharmacists to list the presence or absence of nausea and the number of vomiting for all patients in their charge and record the intervention and display its list.Results: The questionnaire was distributed to 17 inpatients. All patients and pharmacists answered the questionnaire. According to the results of the questionnaire survey of patients, each screen of CINVePRO received a good evaluation that mentioned it was “easy to understand,” “easy to use,” and “especially useful for communicating one’s symptoms.” In addition, the results of a questionnaire survey of the pharmacists revealed that the system was rated as easy to check the patients’ symptoms and practical to use.Conclusion: CINVePRO-PMS was evaluated as a convenient and applicative system. However, linking CINVePRO to the electronic medical record of each hospital is necessary for sharing it among multiple professions.