Evolution of Asthma Concept and Effect of Current Asthma Management Guidelines.
10.4168/aair.2010.2.3.172
- Author:
Sohei MAKINO
1
;
Hironori SAGARA
Author Information
1. Dokkyo Medical University, Tochigi, Japan. makinosoh@ac.auonenet.jp
- Publication Type:Review
- Keywords:
Asthma;
concept;
guideline;
airway remodeling
- MeSH:
Aged;
Airway Remodeling;
Asthma;
Humans;
Hypersensitivity;
Inflammation;
Japan;
Publications
- From:Allergy, Asthma & Immunology Research
2010;2(3):172-176
- CountryRepublic of Korea
- Language:English
-
Abstract:
Concept of asthma has changed from symptom-complex or airway hypersensitivity to airway inflammation and airway remodeling. Based on this concept asthma management guidelines (JGL) has been developed in Japan. Death from asthma has decreased drastically since the publication of the guidelines, although it is still high in elderly population. Further works are expected for "zero-death" from asthma and for tighter control of airway inflammation and resultant airway remodeling.
