Clinical characteristics of several patients with coronavirusdisease 2019 in Lanzhou City

Tao Feng; Hongmei Yue; Jiayuan PU; Jianming HU; Xiaoya Wang; Wenqiang LU; Long LI; Weiying Liu; Xue Bai

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Clinical characteristics of several patients with coronavirusdisease 2019 in Lanzhou City

VernacularTitle:兰州市部分新型冠状病毒肺炎患者病例特征
Author: Tao FENG ^{1
,

2} ; Hongmei YUE ^{1
,

2} ; Jiayuan PU ¹ ; Jianming HU ¹ ; Xiaoya WANG ¹ ; Wenqiang LU ¹ ; Long LI ¹ ; Weiying LIU ¹ ; Xue BAI ¹
Author Information

1. Department of Respiratory and Critical Care Medicine, The First Hospital of Lanzhou University, Lanzhou 730000
2. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China
Publication Type:Journal Article
Keywords: coronavirus disease 2019 (COVID-19); epidemiology; clinical manifestation; imaging feature
From: Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(1):113-117
CountryChina
Language:Chinese
Abstract: 【Objective】 To investigate and summarize the clinical and imaging features of a few patients with coronavirus disease 2019 (COVID-19) in Lanzhou City. 【Methods】 We carried out a retrospective analysis of the epidemiological data, laboratory results and clinical imaging features of eight hospitalized patients with confirmed COVID-19 in The First Hospital of Lanzhou University from January 23 to February 23, 2020. 【Results】 The sex ratio (men to women) of the 8 patients was 5∶3 while their age ranged from 24 to 57 years old. The incubation period was 1-10 days. Of the 8 patients, 7(87.5%) had COVID-19 brought in from other places in China and 1(12.5%) was a secondary infection case. The main clinical manifestations included cough in 6 cases (75%), fever in 4 cases (50%), expectoration in 3 cases (37.5%), and fatigue in 2 cases (25%). All the 8 cases indicated abnormal manifestations in blood routine examinations, 4 cases (50%) decreased in WBC, 7 cases (87.5%) decreased in Lym count, 5 cases (62.5%) increased in LDH, 1 case (12.5%) increased in CK, 1 case(12.5%) increased in CK-MB, 4 cases (50%) increased in CRP, 2 cases (25%) increased in PCT, and 1 case (12.5%) increased in D-dimer. Of the 2 patients examined by chest digital radiography (DR), one DR finding was not typical and the other one suggested increased bilateral lung markings. Six patients were examined by HRCT, of whom four (50%) showed multiple ground glass opacities on both lobes and two (25%) showed multiple ground glass opacities only on the right lobe; none of the 6 imaging findings suggested pleural effusion. Six patients were discharged from hospital after being cured and 1 patient still underwent treatment. 【Conclusion】 Most of these 8 patients had COVID-19 imported from outside the city, and the patients were relatively young with few underlying diseases. Their major symptoms were fever, cough, and expectoration. All of them exhibited abnormal findings in blood routine examinations; half of them suggested increased CRP while a few ones showed abnormal CK and Ddimer values. The imaging manifestations of most patients were multiple ground glass opacities near the peripheral pleura.