Relationship between rapid eye movement sleep and incidence of angina pectoris in different genders

Huimin LI; Bin Yan; Yajuan Fan; Wei Wang; Jian Yang; Xiancang MA

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Relationship between rapid eye movement sleep and incidence of angina pectoris in different genders

VernacularTitle:快速眼球运动睡眠时间与心绞痛在不同性别中的相关性分析
Author: Huimin LI ¹ ; Bin YAN ¹ ; Yajuan FAN ¹ ; Wei WANG ¹ ; Jian YANG ¹ ; Xiancang MA ¹
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1. Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
Publication Type:Journal Article
Keywords: angina pectoris; REM sleep time percentage; polysomnography; female
From: Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(2):267-271,279
CountryChina
Language:Chinese
Abstract: 【Objective】 To investigate the relationship between rapid eye movement sleep (REM) and the incidence of angina pectoris (AP) in different genders. 【Methods】 We recruited 2710 participants from the Sleep Heart Health Study with an average age of (61.7±10.9)y, of whom 1 103 (40.7%) were male and 1 607(59.3%) were female. The participants were divided into grade 1 (<20%), grade 2 (20%-25%), and grade 3 (>25%) according to the percentage of REM sleep time (REM%). Complete polysomnography data and medical records were collected for all the participants. Multivariate logistic regression analysis was used to characterize the independent association between REM% and the occurrence of AP. 【Results】 REM% in the three groups varied significantly in age, body mass index (BMI), smoking, AHI, diabetes, and hypertension (P<0.05). In addition, the incidence of AP in patients with grade 3 of REM% was significantly higher than those with grade 1 and 2 in both men and women. After adjusting for covariates such as age, ethnicity, AHI, marital status, education level, BMI, diabetes, hypertension, and smoking status, multiple logistic regression analysis showed that REM% >25% in women was closely related to AP (OR=1.523; 95% CI:1.132-2.051, P=0.006). 【Conclusion】 Participants with REM sleep time >25% have a significantly increased prevalence of AP in women, but not in men.