Association between fatty acid consumption and hypertension among rural residents in Hanzhong of Shaanxi Province

Ruru Liu; Hong Yan; Yaling Zhao; Qiang LI; Xin Wang; Han FU; Fei Wang; Chen Chen; Wenhao LI; Shaonong Dang

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Association between fatty acid consumption and hypertension among rural residents in Hanzhong of Shaanxi Province

VernacularTitle:陕西汉中农村居民膳食脂肪酸摄入量与高血压的关系
Author: Ruru LIU ^{1
,

2} ; Hong YAN ³ ; Yaling ZHAO ³ ; Qiang LI ³ ; Xin WANG ¹ ; Han FU ¹ ; Fei WANG ¹ ; Chen CHEN ¹ ; Wenhao LI ¹ ; Shaonong DANG ³
Author Information

1. Department of Disinfection and Infection Control, Xi’an Center for Disease Control and Prevention, Xi’an 710054
2. Department of Epidemiology and Biostatistics, School of Public Health of Xi’an Jiaotong University Health Science Center, Xi’an 710061, China
3. Department of Epidemiology and Biostatistics, School of Public Health of Xi’an Jiaotong University Health Science Center, Xi’an 710061, China
Publication Type:Journal Article
Keywords: fatty acid; hypertension; restricted cubic spline; rural resident
From: Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(4):617-622
CountryChina
Language:Chinese
Abstract: 【Objective】 To evaluate the associations of total fat and fatty acid consumption with the risk of hypertension among rural residents in Hanzhong, Shaanxi Province. 【Methods】 A cross-sectional survey on dietary status with a semi-quantitative food frequency questionnaire was conducted among rural residents aged between 18 and 80 years old in Hanzhong of Shaanxi. Multivariate log-binomial regression models and restricted cubic spline were used to explore the associations of dietary total fat, saturated fatty acid, polyunsaturated fatty acid and monounsaturated fatty acids with hypertension and as well as association between dose and response. 【Results】 A total of 2241 individuals were included, with 774 males and 1467 females. Monounsaturated fatty acid accounted for 51.9% of total dietary fat intake, while the other two fatty acids for 48.1%. The intake of dietary fat and any fatty acid in men was significantly in men higher than in women (P<0.001). Results of multivariable log-binomial regression indicated that after adjustment of energy, socio-demographic and lifestyles, the risk of hypertension reduced significantly in Q4 group, compared with that in Q1 (PR: 0.71, 95% CI: 0.54-0.92; P-trend: 0.022) in females. A nonlinear dose-response relationship between monounsaturated fatty acids and hypertension was detected by restricted cubic spline in women (Pnon-linear<0.01). No association was observed of total fat, saturated fatty acid and polyunsaturated fatty acid with hypertension regardless of the gender. 【Conclusion】 In women, increased consumption of monounsaturated fats might play a positive role in reducing the risk of hypertension. Further research is warranted to verify the rationality of causal inference and break-point.