Advances in research on Chiari malformation

VernacularTitle:Chiari畸形的研究进展
Author: Yichang WANG ¹ ; Miao ZHANG ² ; Baixiang HE ¹
Author Information

1. Department of Neurosurgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
2. Center for Translational Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
Publication Type:Journal Article
Keywords: Chiari malformation; classification; pathogenesis; diagnosis; treatment
From: Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(4):491-496
CountryChina
Language:Chinese
Abstract: Chiari malformation, also known as cerebellar tonsillar hernia, is a congenital developmental anomaly in which the cerebellar tonsils extend downward and protrude into the cervical spinal canal through the foramen magnum. It is a common craniocervical junction malformation. Its pathogenesis is complex and clinical manifestations are diverse. Also Chiari malformation is accompanied by many complications. Its pathogenesis remains not clear; therefore, its treatment is controversial. In recent years, new understanding and great progress have been made in the pathogenesis, diagnosis and treatment of Chiari malformation. In this paper, we discuss the classification, pathogenesis and diagnosis of Chiari malformation. In addition, we summarize the operation of Chiari with the hope to provide some help for further basic and clinical research.