Analysis of intraoperative frozen section diagnosis of 1 263 pulmonary nodules
- VernacularTitle:1 263例肺部结节术中冰冻病理诊断分析
- Author:
Xiang ZHOU
1
;
Xiaolong LIANG
1
;
Bin YOU
2
;
Qing CAO
1
;
Hongmiao LIU
1
;
Hongying ZHAO
1
;
Xue LI
1
Author Information
1. Department of Pathology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, P. R. China
2. Department of Chest Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, P. R. China
- Publication Type:Journal Article
- Keywords:
Pulmonary nodules;
lung shadow;
intraoperative frozen section diagnosis;
postoperative paraffin section diagnosis;
malignant pulmonary tumor
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(01):78-84
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the key points and difficulties of intraoperative frozen section diagnosis of pulmonary diseases. Methods The intraoperative frozen section and postoperative paraffin section results of pulmonary nodule patients in Beijing Chaoyang Hospital, Capital Medical University from January 2021 to January 2022 were collected. The main causes of misdiagnosis in frozen section diagnosis were analyzed, and the main points of diagnosis and differential diagnosis were summarized. Results According to the inclusion criteria, a total of 1 263 frozen section diagnosis results of 1 178 patients were included in the study, including 475 males and 703 females, with an average age of 58.7 (23-86) years. In 1 263 frozen section diagnosis results, the correct diagnosis rate was 95.65%, and the misdiagnosis rate was 4.35%. There were 55 misdiagnoses, including 18 (3.44%) invasive adenocarcinoma, 17 (5.82%) adenocarcinoma in situ, 7 (35.00%) mucinous adenocarcinoma, 4 (2.09%) minimally invasive adenocarcinoma, 3 (100.00%) IgG4 related diseases, 2 (66.67%) mucinous adenocarcinoma in situ, 1 (16.67%) atypical adenomatous hyperplasia, 1 (14.29%) sclerosing pulmonary cell tumor, 1 (33.33%) bronchiolar adenoma, and 1 (100.00%) papillary adenoma. Conclusion Intraoperative frozen section diagnosis still has its limitations. Clinicians need to make a comprehensive judgment based on imaging examination and clinical experience.
