Concordance of acid-fast stain result and histopathologic vs clinical diagnosis of leprosy: A three-year retrospective study in a Tertiary Government Hospital and Sanitarium in the Philippines
https://doi.org/10.47895/amp.vi0.8317
- Author:
John Benjamin B. Gochoco
1
;
Andrea Marie Bernales-Mendoza
1
,
2
Author Information
1. Department of Dermatology, Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium, Caloocan City, Philippines
2. Department of Dermatology, Jose R. Reyes Memorial Medical Center, Manila, Philippines
- Publication Type:Journal Article
- Keywords:
Hansen’s Disease;
Concordance;
Slitskin smear;
Skin biopsy;
Histopathology;
Clinical diagnosis;
Descriptive study
- MeSH:
Leprosy;
Biopsy
- From:
Acta Medica Philippina
2024;58(Early Access 2024):1-7
- CountryPhilippines
- Language:English
-
Abstract:
Objectives:In the Philippines, there has been a lack of information on the concordance between classifications
of Hansen’s disease or leprosy clinically, histopathologically, and with AFS results. The study ultimately aimed to
determine the concordance between the clinical diagnosis, histopathological results, and AFS results of patients with leprosy seen at the Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium (DJNRMHS).
Methods:This is a descriptive, retrospective, single-center study conducted at the DJNRMHS, a tertiary government hospital and one of the last remaining sanitaria in the country located in northern Metro Manila in the Philippines. The study reviewed and included all the patient records from the years 2017-2019 which included skin biopsy results and slit-skin smear with AFS. Leprosy patients were then classified based on the following classifications: World Health Organization (WHO) and Ridley-Jopling classifications; and the concordance of clinical diagnosis vs the histopathologic findings and clinical diagnosis vs AFS results were determined using kappa testing.
- Full text:8317-Article Text-143164-1-10-20240202.pdf
