Non-targeted screening of emerging contaminants in drinking water based on high-resolution mass spectrometry
10.19428/j.cnki.sjpm.2023.23043
- VernacularTitle:生活饮用水中新兴污染物高分辨质谱非靶向筛查
- Author:
Linying WU
1
;
Chao FENG
2
;
Guoquan WANG
2
;
Dongliang XUAN
1
;
Yu’e JIN
2
;
Qian PENG
1
;
Dasheng LU
2
Author Information
1. Jiading District Center for Disease Control and Prevention， Shanghai 201800， China
2. Shanghai Municipal Center for Disease Control and Prevention， Shanghai 200336， China
- Publication Type:Journal Article
- Keywords:
high resolution mass spectrometry;
non-targeted screening;
drinking water;
emerging contaminant;
pesticide;
perfluorinated compound
- From:
Shanghai Journal of Preventive Medicine
2023;35(12):1246-1252
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo establish a non-targeted screening method for emerging contaminants in drinking water based on high-resolution mass spectrometry and apply it to actual water samples. MethodsA total of 9 drinking water samples collected from 3 reservoirs in Shanghai were purified and concentrated by HLB solid phase extraction column， then separated and analyzed by liquid chromatography high-resolution mass spectrometer and gas chromatography high⁃resolution mass spectrometer. The acquired data were analyzed by Thermo Tracefinder， Excel and other software combined with mzCloud and NIST databases. The methodology was verified with representative compound standards. Pesticide and perfluorinated compounds were taken as examples to analyze their pollution status. ResultsA non-targeted analysis strategy based on liquid chromatography and gas chromatography tandem high-resolution mass spectrometry was established. The pollution level of 20 kinds of pesticides and 4 kinds of perfluorinated compounds identified in 9 drinking water samples were higher in the Huangpu River than in the Yangtze River estuary. ConclusionThe established non-targeted screening method by high-resolution mass spectrometry can detect potential emerging contaminants in drinking water without relying on the standards， which provides a powerful technical means for water quality monitoring and risk assessment.
