Biological Activities of Sesquiterpenoids： A Review
10.13422/j.cnki.syfjx.20231412
- VernacularTitle:倍半萜类化合物生物学活性研究进展
- Author:
Liyuan YANG
1
;
Ju CHENG
2
;
Jianjun CHEN
3
;
Xiaozheng CHEN
1
;
Xiaoyi SHI
1
;
Rasheed AMNA
2
;
Wenjing SHI
2
;
Xiuzhu LIU
1
;
Xiaodong XIE
1
Author Information
1. Gansu University of Chinese Medicine， Lanzhou 730000， China
2. Institute of Genetics， School of Basic Medicine， Lanzhou University， Lanzhou 730000， China
3. State Key Laboratory of Applied Organic Chemistry， Lanzhou University， Lanzhou 730000， China
- Publication Type:Journal Article
- Keywords:
sesquiterpenoids;
traditional Chinese medicine;
natural compounds;
biological activity;
mechanism
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(5):289-298
- CountryChina
- Language:Chinese
-
Abstract:
Sesquiterpenoids are natural compounds composed of 15 carbon atoms， which can be divided into sesquiterpene alcohols， ketones， lactones， aldehydes， and carboxylic acids according to oxygen groups. These compounds are widely distributed in nature， and their physiological activities are diverse. For example， many sesquiterpenes with potential anticancer effects have been found for anti-tumor effects， including cytotoxicity， antioxidant， immune regulation， cell proliferation， and so on. In addition， some sesquiterpenoids have good application prospects in antibacterial， anti-inflammatory， and anti-cardiovascular diseases. Malignant tumors， inflammation， bacterial diseases， and cardiovascular diseases are the main diseases that cause human death， and natural products have unique advantages in the treatment of these diseases. Therefore， the development of new drugs that are easy to promote has become a new research hotspot. In this paper， the sesquiterpenes extracted from the natural components of Chinese herbs and plants with anti-tumor， anti-inflammatory， antibacterial， and anti-cardiovascular activities， such as Xanthium， Atractylodes， Convolvulus， Acanthium， Ligularia， Artemisia， Ligularia， Ligularia， Labiaceae Mint， Acanthophyllum， Turmeria， Ginger， and other Chinese herbs and plants， were discussed. The biological activities and related mechanisms of this compound were reviewed， which provided a reference for further research and clinical application of sesquiterpenes.
