Treatment of Bone and Joint Diseases with Gancao Fuzitang： A Review
10.13422/j.cnki.syfjx.20232293
- VernacularTitle:经典名方甘草附子汤治疗骨关节病的研究进展
- Author:
Bin LIU
1
;
Chuanhao CHENG
1
;
Yanwu ZHANG
1
;
Zhenghui CHANG
1
;
Tao DUAN
1
Author Information
1. College of Traditional Chinese Medicine， Henan University of Chinese Medicine， Zhengzhou 450046， China
- Publication Type:Journal Article
- Keywords:
bone and joint diseases;
Gancao Fuzitang;
mechanism of action;
clinical application;
research progress
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(5):282-288
- CountryChina
- Language:Chinese
-
Abstract:
Gancao Fuzitang originates from the Treatise on Febrile Diseases and Miscellaneous Diseases （《伤寒杂病论》） and is mainly used to treat pain in the bones and joints and symptoms such as no flexion or extension. It has the effect of tonifying the spleen and kidney and removing dampness and turbidity， so it is widely used in the clinical treatment of various bone and joint diseases. This article reviewed the clinical research and mechanism of Gancao Fuzitang in the treatment of bone and joint diseases. The research has found that this prescription has good efficacy in treating bone and joint diseases such as rheumatoid arthritis， rheumatoid arthritis， ankylosing spondylitis， gout， and intervertebral disc herniation. Its mechanism of action may be related to regulating the level of inflammatory factors， antioxidation， and the protein expression of inflammatory and apoptotic cell-related pathways， improving bone and joint diseases， and alleviating related symptoms. This study can provide a reference for further deepening the research on the prevention and treatment of bone and joint diseases with Gancao Fuzitang.
