Clinical Application and Quality Analysis of Classical Formula Xiaoyaowan: A Review
10.13422/j.cnki.syfjx.20240393
- VernacularTitle:经典方剂逍遥丸临床应用及其质量分析研究进展
- Author:
Weifang DENG
1
;
Xiaohua PEI
2
Author Information
1. Shanxi University of Chinese Medicine,Jinzhong 030619,China
2. Xiamen Hospital,Dongzhimen Hospital,Beijing University of Chinese Medicine,Xiamen 361015,China
- Publication Type:Journal Article
- Keywords:
Xiaoyaowan;
soothing liver and invigorating spleen;
clinical effects;
quality analysis;
quality marker(Q-Marker);
review
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(5):272-281
- CountryChina
- Language:Chinese
-
Abstract:
Xiaoyaowan has the effects of soothing the liver, invigorating the spleen, regulating menstruation, and nourishing blood. It is often used to treat the distending pain of the chest and hypochondriac, loss of appetite, dizziness, and irregular menstruation caused by liver depression and spleen deficiency. The formula originated from the Sinisan of Treatise on Cold Damage(《伤寒论》) in the Han dynasty and was officially formulated in the Song dynasty's Taiping Royal Prescriptions(《太平惠民合计局方》). In the Ming and Qing dynasties, it was developed into more comprehensive formulas such as modified Bazhentang, modified Xiaoyaowan, and other formulas. In recent years, Xiaoyaowan has become a classic formula for treating many symptoms of liver depression. The Pharmacopoeia of the People's Republic of China(《中华人民共和国药典》), 2020 edition, records Xiaoyaowan and modified Xiaoyaowan. Modern clinical research has further expanded the therapeutic range of this formula. Through literature research, it is found that there are certain reports on the clinical application and quality analysis of Xiaoyaowan, but the relevant literature lacks collation so far. Therefore, relevant literature was consulted and sorted out. The paper summarized the treatment of mammary hyperplasia, depression, irregular menstruation, melasma, menopausal syndrome, and polycystic ovary syndrome with Xiaoyaowan, as well as the quality analysis of paeoniflorin, ferulic acid, and glycyrrhizinic acid of Xiaoyaowan. It is expected to lay a foundation for further research on clinical application, pharmacodynamic mechanism, and quality control of this classic formula.