Resting-state Network of Brain in Leukoaraiosis Patients: A Magnetic Resonance Imaging Study
- VernacularTitle:脑白质疏松患者静息态脑网络磁共振成像的研究
- Author:
Na WEI
;
Hao YAN
;
Li-jun BAI
;
Jing-fan YAO
;
Yue-xiu LI
;
Hong-yan CHEN
;
Yu-mei ZHANG
- Publication Type:Journal Article
- Keywords:
leukoaraiosis, resting-state network, default mode network, functional magnetic resonance imaging, independent component analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;21(7):793-798
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diversity of resting-state network of brain between the patients with leukoaraiosis and the healthy people. Methods 31 patients with leukoaraiosis (patients) and 27 healthy persons (controls) were checked with resting-state functional magnetic resonance imaging (rs-fMRI), and analyzed with the independent component analysis (ICA) to explore the resting-state functional brain network. Results The resting-state brain network was found in both the patients and the controls, which was coincident with the previous studies. The active areas were the same in both groups, and the activation was weaken in the patients than in the controls, especially in quadrate gyri, posterior cingulate cortex, superior temporal gyrus, superior parietal gyrus, anterior central gyrus, post central gyrus, insula and prefrontal cortex. Conclusion There is a significant diversity of resting-state network of brain between the patients with leukoaraiosis and healthy people in the activation of active areas.
