Synchronous Primary Parosteal Osteosarcoma and Primary Mediastinal Germ Cell Tumour with Atypical Mycobacterial Infection – A Rare Phenomenon: A Case Report
https://doi.org/10.5704/MOJ.2303.023
- Author:
Lim CH
1
;
Mohamed-Haflah NH
1
;
Abdullah-Sani MH
1
;
Loh CK
2
;
Abdul-Rahman MR
3
Author Information
1. Department of Orthopaedic and Traumatology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
2. Department of Paediatrics, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
3. Department of Surgery, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
- Publication Type:Case Reports
- Keywords:
germ cell tumour, mediastinal, parosteal osteosarcoma, synchronous, tuberculosis
- From:Malaysian Orthopaedic Journal
2023;17(No.1):188-192
- CountryMalaysia
- Language:English
-
Abstract:
Mediastinal germ cell tumours are a rare group of
extragonadal germ cell tumours with less than 5%
prevalence of all germ cell tumours. Primary mediastinal
germ cell tumours themselves account for 16-36% of the
extragonadal germ cell tumours. Along the spectrum of
osteosarcoma, parosteal osteosarcoma is a welldifferentiated surface osteosarcoma with a prevalence of 4%
of all osteosarcoma. As such synchronous primary parosteal
osteosarcoma and primary mediastinal germ cell tumour are
exceedingly rare. This leads to complexity in determining the
most appropriate chemotherapy for two different types of
tumours and its potential side effects of reduced immunity
leading to potential secondary infection. Here we report a
case of a 16-year-old boy who presented with synchronous
primary osteosarcoma and primary mediastinal germ cell
tumour, complicated with atypical mycobacterial infection
post-operatively. Additionally, we discuss our choice of
chemotherapy and the management of the atypical
mycobacterial infection.
- Full text:16.2023my1310.pdf
