Early versus delayed post-therapy whole body scintigraphy for well-differentiated thyroid carcinoma: A meta-analysis
- Author:
Mary Amie Gelina E. Dumatol
1
;
Jessica Elise A. Kuizon
1
;
Michele D. Ogbac
1
Author Information
1. Nuclear Medicine Division, Philippine Heart Center
- Publication Type:Journal Article
- Keywords:
Post-therapy whole body scintigraphy (WBS);
Iodine-131 (I-131)l;
Radioactive Iodine (RAI) Therapy
- MeSH:
Iodine-131;
Thyroid Neoplasms;
Iodine Radioisotopes;
Radionuclide Imaging
- From:
The Philippine Journal of Nuclear Medicine
2023;18(2):32-43
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:No clear consensus exists as to the optimal timing for conducting whole body scintigraphy (WBS) after
radioactive iodine (RAI) therapy for differentiated thyroid carcinoma.
Objective:This study aimed to compare the utility of early versus delayed post-therapy WBS in identifying residual lesions and metastases.
Methods:A systematic review of existing literature was done, yielding 6 observational studies relevant to the subject. Meta-analyses were done comparing lesion detecting rates of early (3-4 days post-RAI) and delayed (7-11 days post-RAI) post-therapy WBS for thyroid remnants and metastases in the lymph nodes, lungs, and bone using a random-effects model with odds ratios (OR) and 95% confidence intervals (CIs). A subgroup analysis was also done relating to the type of collimator used in imaging.
- Full text:18 (2) article 4.pdf
