Research progress on the role of urothelial somatic mutations in the occurrence and recurrence of bladder cancer
10.3969/j.issn.1009-8291.2023.02.019
- VernacularTitle:尿路上皮体细胞突变在膀胱肿瘤发生和复发中作用的研究进展
- Author:
Mingguo ZHOU
1
;
Kaijie WU
1
Author Information
1. Department of Urology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
- Publication Type:Journal Article
- Keywords:
bladder cancer;
somatic mutation;
tumor recurrence;
multifocal tumor;
mutation characteristics
- From:
Journal of Modern Urology
2023;28(2):166-170
- CountryChina
- Language:Chinese
-
Abstract:
Bladder cancer is characterized by high incidence and high recurrence; however, the mechanism of pathogenesis, especially of recurrence is still unclear. This paper reviews the molecular characteristics of bladder cancer, urothelial somatic mutation, driver genes and mutation characteristics, and prospects the future research directions.
