Effects of 450 nm diode blue laser on the vaporization and incision of renal pelvis tissue ex vivo
10.3969/j.issn.1009-8291.2023.02.017
- VernacularTitle:450 nm半导体蓝激光对肾盂组织汽化切割效应的离体动物实验研究
- Author:
Guoxiong LIU
1
,
2
;
Xiaofeng XU
3
;
Dali JIANG
1
;
Xinyang WANG
1
;
Ximin QIAO
3
;
Dalin HE
1
;
Kaijie WU
1
Author Information
1. Department of Urology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061
2. Department of Urology, Xianyang Central Hospital, Xianyang 712000, China
3. Department of Urology, Xianyang Central Hospital, Xianyang 712000, China
- Publication Type:Journal Article
- Keywords:
450 nm blue laser;
renal pelvis tissue;
ex vivo studies;
tissue effect;
precision vaporization
- From:
Journal of Modern Urology
2023;28(2):157-160
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the effects of 450 nm diode blue laser on the morphological changes and thermal damage of renal pelvis under different conditions. 【Methods】 An ex vivo study was conducted on a fresh porcine pelvis model (7 cm×5 cm×3 cm). The laser fiber was fixed on the mechanical arm perpendicular to the renal pelvis tissue, and the distance between them was 1-2 mm. The renal pelvis tissue was incised at a speed of 1-2 mm/s and power of 5-30 W. After the incised tissue was fixed in formalin (4%), the morphology, depth, width and coagulation thickness were observed with naked eyes and a microscope. 【Results】 The different powers had different vaporization and incision effects. When the operating distance was 2 mm, the speed was 2 mm/s and power was 5 W, the vaporization depth, width and coagulation thickness were approximately 0 9 mm, 0.25 mm and 0.35 mm, respectively. With the increase of power, the vaporization width and depth increased, and the coagulation thickness was 0.35-0.50 mm. When the power was more than 10 W, the renal pelvis tissue was easily penetrated. When the laser power was 20 W, the section of the renal pelvis showed an irregular shape of vaporization. When the operating distance was 1 mm, the whole renal pelvis tissue was easily vaporized. When it was 2 mm, a wide and safe energy treatment window was produced. 【Conclusion】 The 450 nm diode blue laser can vaporize and incise renal pelvis tissue safely and effectively, with high precision and little thermal damage. It is expected to be a new surgical tool in the treatment of renal pelvis lesions.
