Clinical characteristics and survival analysis of patients with clear cell papillary renal cell carcinoma based on SEER database
10.3969/j.issn.1009-8291.2023.02.012
- VernacularTitle:基于SEER数据库的肾透明细胞乳头状肾细胞癌患者临床特征及生存分析
- Author:
Zibao XING
1
;
Yi ZHOU
1
;
Jinyu LI
1
Author Information
1. Department of Urology, The 909th Hospital of the Joint Logistic Support Force (Dongnan Hospital of Xiamen University), Zhangzhou, 363000, China
- Publication Type:Journal Article
- Keywords:
renal tumor;
clear cell papillary renal cell carcinoma;
clinical characteristics;
survival analysis;
prognosis
- From:
Journal of Modern Urology
2023;28(2):137-140
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To evaluate the clinical characteristics and survival of patients with rare clear cell papillary renal cell carcinoma (ccpRCC). 【Methods】 Clinical data of ccpRCC cases treated during 2016 and 2019 were analyzed, clinical characteristics were described, and survival was analyzed using the Kaplan-Meier method. 【Results】 In the SEER database, 191 ccpRCC cases with complete clinical data and positive histology were retrieved, including 112 males (58.7%) and 79 females (41.3%), 136 Grade 1-2 (71.2%) cases and 19 Grade 3-4 (10.0%) cases, 174 stage T1 (91.1%) cases and 17 stage T2-3 (8.9%) cases. Distant metastasis (lung metastasis combined with lymph node involvement and major vein involvement) occurred in one case, and vein tumor thrombosis occurred in two patients. Surgery especially radical nephrectomy and partial nephrectomy was performed in 181 patients (94.8%). One patient died due to recurrence, and 4 due to other causes. The 12-month and 24-month survival were 98.5% and 97.4%, respectively. 【Conclusion】 Patients with ccpRCC have low clinical stage and histological grade, minimal tumor progression and distant metastasis, good prognosis and extremely low disease-specific mortality. Radical nephrectomy and partial nephrectomy have significant therapeutic effects.
