CRP is an important factor affecting the timing of surgical drainage of ureteral calculi with upper urinary tract infection
10.3969/j.issn.1009-8291.2023.05.010
- VernacularTitle:C-反应蛋白是输尿管结石伴上尿路感染外科引流时机选择的重要影响因素
- Author:
Fangzhou LI
1
;
Qiang LIU
1
;
Dongdong XIAO
1
;
Zhebin DU
1
;
Hanqing XUAN
1
;
Qi CHEN
1
;
Lianhua ZHANG
1
Author Information
1. Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
- Publication Type:Journal Article
- Keywords:
ureteral calculi with infection;
emergency treatment;
surgical drainage;
c-reactive protein;
biomarkers
- From:
Journal of Modern Urology
2023;28(5):417-420
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the timing of surgical drainage for ureteral calculi with upper urinary tract infection. 【Methods】 Clinical data of 117 cases of ureteral calculi with upper urinary tract infection treated in our hospital during Jan.2018 and Jan.2020 were retrospectively analyzed. According to different treatment methods, the patients were divided into surgical drainage group and non-surgical drainage group. The patients’ age, gender, side of calculi, peak body temperature, time of onset, white blood cell (WBC) count, C-reactive protein (CRP) and other clinical indicators were compared between the two groups. The cutoff value of surgical drainage was determined with receiver operator characteristic (ROC) curve. 【Results】 The patients’ age, peak body temperature, WBC count and CRP level were the influencing factors of surgical drainage (P<0.05). Regression analysis showed that CRP (P<0.001), age (P=0.003) and WBC count (P=0.014) were independent risk factors for surgical drainage. The area under the ROC curve (AUC) of CRP, age, and WBC count were 0.923, 0.601, and 0.796, respectively. The cutoff value of CRP was 29.87 mg/L (sensitivity 79.4%, specificity 90.0%). Logistic regression model showed CRP was a significant clinical predictor. 【Conclusion】 Ureteral calculi with upper urinary tract infection need to be diagnosed and treated in time. Positive anti-infection should be performed during emergency treatment, and surgical drainage could be selected according to the value of CRP.
