Related factors of recurrence of renal cell carcinoma after robot-assisted partial nephrectomy
10.3969/j.issn.1009-8291.2023.05.002
- VernacularTitle:机器人肾部分切术后肾癌复发的相关因素分析
- Author:
Guodong HONG
1
;
Shuanbao YU
1
;
Jinshan CUI
1
;
Zhenhao LI
1
;
Jin TAO
1
;
Yafeng FAN
1
;
Biao DONG
1
;
Xuepei ZHANG
1
,
2
Author Information
1. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052
2. Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou 450052, China
- Publication Type:Journal Article
- Keywords:
robot;
partial nephrectomy;
recurrence;
related factors
- From:
Journal of Modern Urology
2023;28(5):372-376
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the recurrence of patients with renal cell carcinoma (RCC) after robot-assisted partial nephrectomy (RAPN), and to explore the related factors of recurrence. 【Methods】 Clinical data of 367 RCC patients who underwent RAPN during 2015 and 2020 in our hospital were retrospectively collected. Patients were divided into recurrence group and non-recurrence group. The related factors of recurrence and 5-year cumulative recurrence rate of RCC and clear cell renal cell carcinoma (ccRCC) in the recurrence group were analyzed. 【Results】 The median follow-up was 48 (IQR:38-60) months. Recurrence occurred in 9 patients, with a 5-year cumulative recurrence rate of 97.5%. For RCC patients, univariate analysis showed that tumor size, T-stage, R. E. N. A. L. score, R value, N value, and operation time were significantly associated with postoperative recurrence (P<0.05), while multivariate analysis showed that N value (HR=15.75, 95%CI:2.00-124.17, P=0.009) was an independent related factor. For ccRCC patients, univariate analysis showed that hypertension, tumor size, T-stage, R. E. N. A. L. score, N value, operation time and WHO/ISUP grade were significantly associated with postoperative recurrence (P<0.05), while multivariate analysis showed that WHO/ISUP grade (HR=4.99, 95%CI:1.04-24.01, P=0.045) was an independent related factor. 【Conclusion】 The 5-year cumulative recurrence rate of RCC patients after RAPN is 2.5%. N value and WHO/ISUP grade are the independent related factor of recurrence of RCC and ccRCC, respectively.
