Risk factors of incidental prostate cancer in patients undergoing radical cystoprostatectomy
10.3969/j.issn.1009-8291.2023.06.003
- VernacularTitle:根治性膀胱切除术患者伴偶发前列腺癌的危险因素
- Author:
Abuduaini KAIERMAIDING
1
;
Mulati NAYILA
2
;
Qianjin LI
1
;
Kamili AIKEBAIERJIANG
1
;
Rexiati MULATI
1
Author Information
1. Department of Urology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054
2. First Cliniccil Medical College of Xinjiang Medical University, Urumqi 830054, China
- Publication Type:Journal Article
- Keywords:
bladder cancer;
radical cystoprostatectomy;
incidental prostate cancer;
prostate specific antigen;
risk factor
- From:
Journal of Modern Urology
2023;28(6):469-473
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the risk factors and clinical significance of incidental prostate cancer (IPCa) in patients undergoing radical cystoprostatectomy (PCR). 【Methods】 The clinicopathological data of 260 patients undergoing RCP in our hospital during Jan. 2010 and Jan. 2022 were retrospectively analyzed, including 39 cases of IPCa detected with postoperative pathology, and 221 non-IPCa cases. 【Results】 The detection rate of IPCa was 15%. Univariate logistic regression analysis showed age (P<0.001), smoking (P<0.05), T stage (P<0.05), number of tumors (P<0.05), involvement of trigone (P<0.05), prostate volume (P<0.05), and preoperative total prostate-specific antigen (tPSA) (P<0.05) were influencing factors of prostate cancer. Multivariate logistic regression analysis showed that age (OR=1.061, 95%CI: 1.021-1.107, P=0.004), smoking (OR=2.852, 95%CI: 1.296-6.677, P=0.012), involvement of trigone(OR=2.967, 95%CI: 2.365-3.657, P=0.019) and preoperative tPSA (OR=1.109, 95%CI: 1.011-1.223, P=0.030) were independent risk factors of IPCa. 【Conclusion】 Advanced age, smoking, bladder tumor in trigone and preoperative PSA abnormality are risk factors for incidental prostate cancer in bladder cancer patients.
